Chemoprevention in experimental animals

Scorpion Venom Pisoning in Experimental Animals

Asbestosis in experimental animals.

Previous animal experiments with asbestos dusts have been almost entirely confined to chrysotile asbestos. It was, therefore, decided to investigate the effects of mill dusts from the three types of asbestos that are produced commercially in South Africa, namely chrysotile, amosite, and crocidolite. Chrysotile and amosite samples were relatively pure while in contrast the crocidolite dust was f...

Fasting and Experimental Animals, Detrimental or Positive?

While fasting has been practiced for centuries, its beneficial effects was unknown until recently. This review tries to analyze the current literature of how fasting and intermittent fasting (IF) could affect clinical pathological parameters, learning, mood and brain plasticity. The effects of different ways of fasting on metabolism and stress were also explored. Animal experiments have elucida...

Sepsis Models in Experimental Animals

Sepsis develops as a common inflammatory response to various infections. It runs with the picture of a complex heterogeneous syndrome which often leads to the development of multiple organ dysfunctions and causes the death of millions of people worldwide. For various reasons, detailed research of sepsis in humans is difficult to conduct; therefore, a lot of efforts have been made to model it. P...

Use of experimental animals.

I shall deal briefly this morning with three topics: (1) the different species and strains of animals to be employed in experimental studies-of bowel cancer with asbestos; (2) combinations of carcinogens; and (3) the difficult and debatable tumors that one sees in experimental animals. I am glad to see that in South Africa baboons are also being used. Frequently Wistar rats are used .or rats of...